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 > 【Tau】

Tau信息

英文名称：Microtubule-associated protein tau
中文名称：微管相关蛋白tau
靶点别称：MAPT，MTBT1，Paired helical filament-tau，MAPTL，Microtubule Associated Protein Tau，G Protein Beta1/Gamma2 Subunit-Interacting Factor 1，Protein Phosphatase 1， Regulatory Subunit 103，Neurofibrillary Tangle Protein，PHF-Tau，TAU，Microtubule-Associated Protein Tau， Isoform 4，Microtubule-Associated Protein Tau，PPP1R103，FTDP-17，MTBT2，DDPAC，MSTD，PPND，tau Proteins，MGC138549，FLJ31424
上市药物数量：1
临床药物数量：34
最高研发阶段：批准上市

Tau产品列表

筛选结果
产品库
物种
标签
属性
标记
货号 物种 产品描述 蛋白结构 纯度 活性
TAU-H5117
Human		 Human Tau-441 / 2N4R Protein, Tag Free (MALS verified)
TAU-H51H3
Human		 Human Tau-441 / 2N4R Protein, His Tag
TAU-H5115
Human		 Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free
CHEK-ATP087
Human		 HEK293/Human Tau-K18 (GFP) Stable Cell Line
PT1-Y2073
Mouse		 Monoclonal Anti-Human Phospho-Tau (Thr181) Antibody, Mouse IgG2a (8D8C10)
PT7-Y2074
Mouse		 Monoclonal Anti-Human Phospho-Tau (Thr217) Antibody, Mouse IgM (6G7C8)
TAU-C5113
Cynomolgus		 Cynomolgus Tau Protein, Tag Free
TAU-H5113
Human		 Human Tau-441 K18 (P301L) Pre-formed Fibrils Protein, Tag Free
TAU-H5114
Human		 Human Tau Protein, Tag Free (MALS verified)
TAU-H5116
Human		 Human Tau-441 K18 Pre-formed Fibrils Protein, Tag Free
TAU-H5118
Human		 Human Tau-441 (K18, P301L) Protein, Tag Free (MALS verified)
TAU-H5143
Human		 Human Tau-410 / 2N3R Protein, His Tag (MALS verified)
TAU-H5144
Human		 Human Tau-441 / 2N4R (P301L) Protein, His Tag
TAU-H5145
Human		 Human Tau-441 / 2N4R (P301S) Protein, His Tag (MALS verified)
TAU-H5147
Human		 Human Tau-441 GSK-3beta-phosphorylated protein, His Tag
TAU-H51H4
Human		 Human Tau-441 / 2N4R (241-380) Protein, His Tag (MALS verified)
TAU-H51H5
Human		 Human Tau-441 / 2N4R (273-380) Protein, His Tag (MALS verified)
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Tau分子别名

DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU

Tau分子背景

Tau, the microtubule‐associated protein, forms insoluble filaments that accumulate as neurofibrillary tangles in Alzheimer's disease (AD) and related tauopathies. Under physiological conditions, tau regulates the assembly and maintenance of the structural stability of microtubules. In the diseased brain, however, tau becomes abnormally hyperphosphorylated, which ultimately causes the microtubules to disassemble, and the free tau molecules aggregate into paired helical filaments.

Tau上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

Tau临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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