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 > 【CD3】

CD3信息

英文名称：T cell surface glycoprotein CD3
中文名称：T细胞表面糖蛋白CD3复合体
靶点别称：CD3 Complex
上市药物数量：8
临床药物数量：177
最高研发阶段：申请上市

CD3产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
CDE-M531
Mouse		 Monoclonal Anti-Human CD3 Antibody, Mouse IgG1 (SP34-2)
GMP-MC0323
Mouse		 GMP Monoclonal Anti-Human CD3 Antibody (OKT3)
CD3-FM532
Mouse		 FITC-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG1 (UCHT1) (0.03% Proclin)
CDE-AHFP1
Mouse		 APC-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3)Star Staining
CDE-BV84G0
Mouse		 Biotinylated Anti-Human CD3 Antibody, Mouse IgG2a,Avitag™ (Clone: OKT3), premium grade
CDE-CH44G1
Mouse		 Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), premium grade (CHO)
CDE-F15dP1
Mouse		 FITC-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3)
CDE-M120a
Mouse		 Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), premium grade (HEK)
CDE-M532
Mouse		 Monoclonal Anti-Human CD3 Antibody, Mouse IgG1 (UCHT1)
CDE-PCFP1
Mouse		 PE-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3)Star Staining
FABm001-03
Mouse		 FITC-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3)
HGS-S374
Rabbit		 Recombinant Monoclonal Anti-CD3 Antibody, Rabbit (4B7)
RES-A095
Mouse		 resDetect™ Anti-CD3 Antibody Indirect ELISA Kit (Residue Testing)
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CD3分子别名

CD3

CD3分子背景

CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.

CD3上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

CD3临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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