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 > 【GLP1R】

GLP1R信息

英文名称：Glucagon-like peptide-1
中文名称：胰高血糖素类肽-1
靶点别称：GLP-1
上市药物数量：0
临床药物数量：1
最高研发阶段：临床一期

GLP1R产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
GLR-H82E3
Human		 Biotinylated Human GLP1R Protein, His,Avitag™ (HPLC verified)
GLR-H5253
Human		 Human GLP1R Protein, Fc Tag (MALS verified)
CHEK-ATF096
Human		 Human GLP-1R (Luc) HEK293 Reporter Cell
CHEK-ATP160
Human		 HEK293/Human GLP-1R Stable Cell Line (High Expression)
CHEK-ATP161
Human		 HEK293/Human GLP-1R Stable Cell Line (Medium Expression)
CHEK-ATP162
Human		 HEK293/Human GLP-1R Stable Cell Line (Low Expression)
GLR-H52D4
Human		 Human GLP1R Full Length Protein (L260F), Flag,His Tag (Detergent)
GLR-H52H7
Human		 Human GLP1R Protein, His Tag (MALS verified)
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GLP1R分子别名

GLP-1-R, GLP-1R, glucagon like peptide 1 receptor

GLP1R分子背景

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.

GLP1R临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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