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LAG-3信息

英文名称:Lymphocyte activation gene 3 protein
中文名称:淋巴细胞活化基因3蛋白
靶点别称:Lymphocyte activation gene 3 protein,LAG3,Lymphocyte Activating 3,Lymphocyte-Activation Gene 3,CD223 Antigen,Protein FDC,CD223,LAG-3,FDC,sLAG-3
上市药物数量:1
临床药物数量:29
最高研发阶段:批准上市

Licensing 项目合作

项目名称 药物类型 治疗领域 适应症 阶段 权益地区
LAG-3 mAb 单抗 肿瘤学,癌症 黑色素瘤、晚期淋巴瘤、其它晚期恶性实体肿瘤 临床I期 全球

LAG-3产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
LA3-H82E9
Human
Biotinylated Human LAG-3 / CD223 Protein, His,Avitag™ (MALS verified)
LA3-M52H5
Mouse
Mouse LAG-3 / CD223 Protein, His Tag (MALS verified)
LA3-H5255
Human
Human LAG3 / CD223 Protein, Fc Tag (MALS Verified)
LA3-C5252
Cynomolgus
Cynomolgus LAG-3 / CD223 Protein, Fc Tag (MALS verified)
LA3-C52A0
Cynomolgus
Cynomolgus LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag (HPLC verified)
LA3-C52H7
Canine
Canine LAG-3 / CD223 Protein, His Tag (MALS verified)
LA3-C8258
Cynomolgus
Biotinylated Cynomolgus LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag, ultra sensitivity (primary amine labeling) (MALS verified)
LA3-C82E5
Cynomolgus
Biotinylated Cynomolgus LAG-3 / CD223 Protein, His,Avitag™ (MALS verified)
LA3-C82H3
Cynomolgus
Cynomolgus LAG-3 / CD223 Protein, His Tag
LA3-H5222
Human
Human LAG-3 / CD223 Protein, His Tag (MALS verified)
LA3-H522a
Human
Human LAG-3 / CD223 Protein, His Tag, low endotoxin (MALS verified)
LA3-H525c
Human
Human LAG-3 / CD223 Protein, Llama IgG2b Fc Tag, low endotoxin (MALS verified)
LA3-H52Aa
Human
Human LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag (MALS verified)
LA3-H52H3
Human
Human LAG-3 / CD223 Protein, His Tag (MALS verified)
LA3-H82F3
Human
Biotinylated Human LAG-3 / CD223 Protein, Mouse IgG2a Fc,Avitag™ (MALS verified)
LA3-H82Fb
Human
Biotinylated Human LAG-3 / CD223 Protein, Fc,Avitag™ (MALS verified)
LA3-HP2H4
Human
PE-Labeled Human LAG-3 / CD223 Protein, His TagStar Staining
LA3-M5253
Mouse
Mouse LAG-3 / CD223 Protein, Fc Tag (MALS verified)
LA3-M82E5
Mouse
Biotinylated Mouse LAG-3 / CD223 Protein, His,Avitag™ (MALS verified)
LA3-M82F3
Mouse
Biotinylated Mouse LAG-3 / CD223 Protein, Fc,Avitag™ (MALS verified)
LA3-R52H5
Rat
Rat LAG3 / CD223 Protein, His Tag (HPLC verified)
SCJUR-STF065
Human
Human LAG-3 (Luc) Jurkat Reporter Cell Development Service
ACRO质量管理体系
 
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LAG-3分子别名

LAG3,CD223,FDC

LAG-3分子背景

Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

LAG-3上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

LAG-3临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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