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TROP-2信息

英文名称:Tumor-associated calcium signal transducer 2
中文名称:肿瘤相关钙信号传感器2
靶点别称:Tumor-associated calcium signal transducer 2,M1S1,TROP2,TACSTD2,Pancreatic carcinoma marker protein GA733-1,Tumor Associated Calcium Signal Transducer 2,GA733-1,Membrane Component, Chromosome 1, Surface Marker 1,Gastrointestinal Tumor-Associated Antigen GA7331,Pancreatic Carcinoma Marker Protein GA7331,Cell surface glycoprotein Trop-2,Membrane component chromosome 1 surface marker 1,40kD Glycoprotein, Identified By Monoclonal Antibody GA733,Cell Surface Glycoprotein TROP2,Epithelial Glycoprotein
上市药物数量:1
临床药物数量:19
最高研发阶段:批准上市

抗体项目交易平台

项目名称 项目阶段 分子类型 分子来源 疾病领域 适应症
TROP-2 ADC - 01 IND ADC 鼠源人源化 实体瘤 胰腺癌,乳腺癌

Licensing 项目合作

项目名称 药物类型 治疗领域 适应症 阶段 权益地区
Trop-2 ADC 生物偶联药物 肿瘤学,癌症 难治型癌症(胰腺癌、胃癌) IND Ready 全球

TROP-2产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
TR2-H5223
Human
Human TROP-2 / TACSTD2 Protein, His Tag (MALS verified)
TR2-H82E5
Human
Biotinylated Human TROP-2 / TACSTD2 Protein, His,Avitag™ (MALS verified)
TR2-H5253
Human
Human TROP-2 / TACSTD2 Protein, Fc Tag (MALS verified)
CHEK-ATP036
Human
HEK293/Human TROP-2 Stable Cell Line
MBS-K028
Human
Human TROP-2-coupled Magnetic Beads
TR2-C52H4
Canine
Canine TROP-2 / TACSTD2 Protein, His Tag
TR2-C52H5
Cynomolgus
Cynomolgus TROP-2 / TACSTD2 Protein, His Tag (MALS verified)
TR2-C82E3
Cynomolgus
Biotinylated Cynomolgus TROP-2 / TACSTD2 Protein, His,Avitag™ (MALS verified)
TR2-H52H6
Human
Human TROP-2 / TACSTD2 (88-274) Protein, His Tag
TR2-H82Ea
Human
Biotinylated Human TROP-2 / TACSTD2 (88-274) Protein, His,Avitag™ (MALS verified)
TR2-H82F4
Human
Biotinylated Human TROP-2 / TACSTD2 Protein, Fc,Avitag™
TR2-M52H6
Mouse
Mouse TROP-2 / TACSTD2 Protein, His Tag (MALS verified)
TR2-M82E9
Mouse
Biotinylated Mouse TROP-2 / TACSTD2 Protein, His,Avitag™ (MALS verified)
TR2-M82F3
Mouse
Biotinylated Mouse TROP-2 / TACSTD2 Protein, Fc,Avitag™ (MALS verified)
TR2-R5255
Rhesus macaque
Rhesus macaque TROP-2 / TACSTD2 Protein, Fc Tag (MALS verified)
TR2-R52H3
Rhesus macaque
Rhesus macaque TROP-2 / TACSTD2 Protein, His Tag (MALS verified)
TR2-R52H9
Rabbit
Rabbit TROP-2 / TACSTD2 Protein, His Tag (MALS verified)
TR2-R82E7
Rhesus macaque
Biotinylated Rhesus macaque TROP-2 / TACSTD2 Protein, His,Avitag™ (MALS verified)
TR2-R82F6
Rhesus macaque
Biotinylated Rhesus macaque TROP-2 / TACSTD2 Protein, Fc,Avitag™ (MALS verified)
ACRO质量管理体系
 
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TROP-2分子别名

TACSTD2,GA733-1,M1S1,TROP2

TROP-2分子背景

TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

TROP-2上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

TROP-2临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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