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 > 【BCMA】

BCMA信息

英文名称：B-cell maturation protein
中文名称：B细胞成熟蛋白
靶点别称：B-Cell Maturation Protein，B-Cell Maturation Factor，B Cell Maturation Antigen，CD269 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 17，TNFRSF17，TNFRSF13A，CD269，BCM，BCMA，TNF Receptor Superfamily Member 17，Tumor Necrosis Factor Receptor Superfamily， Member 17，B-Cell Maturation Antigen
上市药物数量：7
临床药物数量：101
最高研发阶段：批准上市

抗体项目交易平台

项目名称 项目阶段 分子类型 分子来源 疾病领域 适应症
BCMA VHH - 01 Lead 单抗 纳米抗体 血液瘤 多发性骨髓瘤,非霍奇金淋巴瘤

Licensing 项目合作

项目名称 药物类型 治疗领域 适应症 阶段 权益地区
CS1+BCMA CAR-T 细胞治疗 肿瘤学,癌症 多发性骨髓瘤 IND Ready 全球（除欧洲、加拿大）

BCMA产品列表

筛选结果
产品库
物种
标签
属性
标记
货号 物种 产品描述 蛋白结构 纯度 活性
BCA-HP2H2
Human		 PE-Labeled Human BCMA / TNFRSF17 Protein, His Tag (Site-specific conjugation)
BCA-H82E4
Human		 Biotinylated Human BCMA / TNFRSF17 Protein, His,Avitag™, premium grade
BCA-HF254
Human		 FITC-Labeled Human BCMA / TNFRSF17 Protein, Fc Tag
BC7-H5254
Human		 Human BCMA / TNFRSF17 Protein, Fc Tag, premium grade
BC7-H82F0
Human		 Biotinylated Human BCMA / TNFRSF17 Protein, Fc,Avitag™, premium grade
BCA-C5253
Cynomolgus / Rhesus macaque		 Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc Tag
BCA-C5257
Cynomolgus / Rhesus macaque		 Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Llama IgG2b Fc Tag (MALS verified)
BCA-C52H3
Canine		 Canine BCMA / TNFRSF17 Protein, His Tag (MALS verified)
BCA-C52H7
Cynomolgus / Rhesus macaque		 Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, His Tag (MALS verified)
BCA-C82E5
Cynomolgus / Rhesus macaque		 Biotinylated Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, His,Avitag™
BCA-C82F4
Cynomolgus / Rhesus macaque		 Biotinylated Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc,Avitag™
BCA-H522y
Human		 Human BCMA / TNFRSF17 Protein, His Tag, premium grade
BCA-H5253
Human		 Human BCMA / TNFRSF17 Protein, Mouse IgG2a Fc Tag, low endotoxin
BCA-H5259
Human		 Human BCMA / TNFRSF17 Protein, Llama IgG2b Fc Tag, low endotoxin
BCA-HA2H4
Human		 APC-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HA2H5
Human		 APC-Labeled Human BCMA / TNFRSF17 Protein, His Tag (Site-specific conjugation)
BCA-HA2H7
Human		 Alexa Fluor™ 555-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HA2H8
Human		 Alexa Fluor™ 488-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HA2H9
Human		 Alexa Fluor™ 647-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HF2H1
Human		 FITC-Labeled Human BCMA / TNFRSF17 Protein, His Tag
BCA-HF2H3
Human		 FITC-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HP2H7
Human		 PE-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-M43
Mouse		 Anti-BCMA Neutralizing Antibody, Mouse IgG1 (recommended for neutralizing assay)
BCA-M5258
Mouse		 Mouse BCMA / TNFRSF17 Protein, Fc Tag
BCA-M52H3
Mouse		 Mouse BCMA / TNFRSF17 Protein, His Tag
BCA-M82F0
Mouse		 Biotinylated Mouse BCMA / TNFRSF17 Protein, Fc,Avitag™
BCA-R52H3
Rat		 Rat BCMA / TNFRSF17 Protein, His Tag
BCA-R52H4
Rabbit		 Rabbit BCMA / TNFRSF17 Protein, His Tag
CEA-B045
Human		 ClinMax™ Human Soluble BCMA ELISA Kit
MBS-C004
Human		 ActiveMax® Human BCMA μBeads, premium grade (for cells)
MBS-K004
Human		 Human BCMA-coupled Magnetic Beads
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BCMA分子别名

TNFRSF17,CD269,BCM,BCMA

BCMA分子背景

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

BCMA上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

BCMA临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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